Can Viagra help stroke patients?

Will soon begin a study that aims to determine whether Viagra or cialis 20 to speed recovery in patients with stroke within seven days or less from its development. The study will be carried out in hospital. Henry Ford (Detroit, USA), for today we have to find 62 more volunteers.

Two years ago, the clinic received approval to use the “little blue pill”, as many call Viagra, in an early pilot study in patients undergoing moderate ischemic stroke – the most common kind of stroke.

The study decided to step up, as far in it was included only 10 patients, said Dr. Brian silver, a neurologist leading the study. Some patients and their families feared the side effects associated with the drug, “inappropriate behavior”, high sexual desire and destructiveness.

The search for new indications for the use of the drug is important for patients and pharmaceutical companies, especially for manufacturers of highly profitable drugs like Viagra, to compensate for the loss after the end of the term of protection of a patent.

In 2005, Pfizer received Federal approval for sale of Viagra in other packaging (white tablets 20 mg) under the name of Revatio for the treatment of pulmonary hypertension in children and adults. Under recommended taken 3 times a day annual cost of therapy, Revatio is around 10 thousand dollars, or 33 dollars per day, which is above the amount spent on erectile dysfunction treatment. The higher cost of single dose of Revatio reflects the cost of Pfizer to study the drug in a completely different group of patients, obtaining Federal approval and marketing.

The representative of Pfizer said that “the company constantly supports clinical research – directly or through independent research grants – to increase knowledge about Pfizer products and promising medical interventions”.

Today conducted more than 25 studies on the usage of Viagra in the treatment of various conditions, from gestational hypertension to menstrual bleeding and heart failure.

Expect that the study in the hospital. Henry Ford built the Foundation of what Viagra can have therapeutic benefits beyond erectile dysfunction, says Michael chopp, the chief neurologist of the hospital.

Dr. COPP examines the ability of the brain to form new blood vessels and neural connections is known as the remodeling process. He first gave Viagra rats to determine whether the drug is on the restoration movements and memory after a stroke. Rats receiving Viagra were able to find the hidden exit of the labyrinth, showed the best work of the limbs when moving on inclined grids and turned in both directions, whereas in animals not treated in post-stroke period Viagra observed motion in one direction only.

Dr. silver suggests that Viagra may produce a molecule cGMP (cyclic guanosine monophosphate) which sends signals to the brain cells to create new nerve cells and Mineralnye connections (synapses).

Clinic patients they. Henry Ford get Viagra daily for two weeks followed by a two week observation period. The first 12 patients were prescribed 25 mg of the drug; each subsequent group of patients for 12 people will get a dose higher than the previous until reaching 150 mg twice a day. The study is randomized and controlled, so that half the patients in the first phase will receive a placebo.

Leave a Reply