According to a recent study conducted at the University Underbite (Vanderbilt University), a special protein inside certain immune system cells blocks the growth process of the bacteria Staphylococcus due to the “absorption” of manganese and zinc.
One of the ways to protect from bacteria is hiding food from them, in particular, metals that are necessary for the bacteria to live. The result is a protein that absorbs metals such as manganese and zinc that can protect the body from the harmful effects of bacteria, experts say.
The results of the study were published in the latest issue of the journal Science. According to the researchers, the results can become the basis for important therapeutic method of combating local bacterial infections. A new treatment strategy is necessary to combat the growing number of infectious diseases, which end fatal for the patient. In particular, the obtained results will help to develop effective therapy for antibiotic-resistant modifications of Staphylococcus aureus (Staphylococcus aureus) — MRSA.
Statistics indicate that the mortality rate in the USA from MRSA infection is higher than from HIV/AIDS. “Modification of Staphylococcus aureus is the most dangerous pathology of bacterial origin that affects the inhabitants of America,” says Dr. Eric Skaare (Eric Skaar), Professor of Microbiology and immunology, head of the research project. The statistics have prompted scientists to develop effective methods of treatment of this disease.
The researchers suggested that the proteins outside the bacterium Staphylococcus aureus, may play an important role in the process of combating the infection and the human immune system. “So how can we say exactly where the infection, it is possible to consider the proteins that are in the vicinity of the source of infection,” says Dr. Skaare. Using sophisticated technology, which is called “spectrometry displayed mass” (mass spectrometry imaging), researchers have identified many proteins that act in a specific way in the field of bacterial activity in the organisms of sick mice. A group of scientists managed to demonstrate that a protein Calprotectin inhibited the growth of staph bacteria due to the “food” for bacteria, metals magnesium and zinc.