The vaccine in the polymer film: technology of the future is already a reality

In many cases, physicians have ceased to satisfy the classic methods of vaccination, when to generate the acquired immune system uses proteins of viruses or bacteria. Method of DNA vaccination greatly improves the result and does not require injections.

The knowledge of the mysteries of germs and viruses at the cellular level helped to create and now widely used vaccines are based on “acquaintance” of the human immune system with a weakened or killed pathogen. As a result, the blood appears specific antibodies that protect the organism during the invasion of real aggressor.

However, immune reaction, occurs when this method of vaccination is not always reliable enough – a good example of this is not 100% effective vaccination against influenza.

The creation of a fundamentally new method of DNA vaccination was made possible after scientists penetrated the secrets of the pathogens at the molecular level. DNA vaccines, as the name implies, acquaints the immune system with proteins of the pathogen, and with the elements of its hereditary material – genes.

Such vaccines are able to create almost life-long immunity, they are already cheaper to manufacture, do not require storage at low temperature and have many other advantages compared with classical drugs for immunization.

Now to these positive qualities of DNA vaccines added another – extremely convenient method of introducing a drug into the body that requires no injections, no syringes.

American scientists from mit (Massachusetts Institute of Technology) have developed a method allowing to introduce the DNA vaccine slowly over hours, days and even weeks.

Square sticker, resembling in appearance a piece of plaster, composed of many layers of special polymer film, between which are placed molecules and molecules of the vaccine. The sticker is supplied on the surface of hundreds of microneedles that pierce the skin to a depth of 0.5 mm. This allows the released vaccine will come in contact with immune system cells in the epidermis, but the length of the needles is not enough to impact the pain receptors.

Slow release of the vaccine ensures the formation of specific immunity.

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